Pentoxifylline Use in Dermatology

Author(s): Seray Kulcu Cakmak, Atil Cakmak, Muzeyyen Gonul, Arzu Kilic, Ulker Gul.

Journal Name: Inflammation & Allergy - Drug Targets (Discontinued)

Volume 11 , Issue 6 , 2012

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Abstract:

Pentoxifylline is methylxanthine derivative which is used in microcirculatory disorders as a vasoactive drug. Novel immunomodulatory properties of pentoxifylline have been reported including the down regulation of tumour necrosis factor-α synthesis and other inflammatory cytokines. Studies have shown that pentoxifylline might be efficacious in a wide spectrum of skin diseases. This article focuses on the use of pentoxifylline which is a safe and cheap drug in various dermatological disorders.

Keywords: Dermatology, disorder, pentoxifylline, treatment, tumor necrosis factor-α inhibitor, Anti-inflammatory, Venous ulcers, Behcet’s Disease, Recurrent Aphthous Stomatitis, Vasculopathy, Cutaneous Leishmaniasis

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Article Details

VOLUME: 11
ISSUE: 6
Year: 2012
Page: [422 - 432]
Pages: 11
DOI: 10.2174/187152812803590028
Price: $58

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