Here we demonstrate the synthesis of various derivatives of 5-(6-substituted phenyl-2H-chromen-3-yl)-
oxazoles 5(a-k) by using Suzuki coupling conditions with different substituted boronic acids and obtained 23-57 % yields.
We also synthesised various derivatives of the 5-(substituted 2H-chromen-3-yl)-oxazoles 3(a-j) mediated by TOSMIC as
a reagent and achieved 58-70 % yield.
Keywords: 5-(substituted 2H-chromen-3-yl)-oxazoles, 5-(6-substituted phenyl-2H-chromen-3-yl)-oxazoles, suzuki coupling,
TOSMIC reagent, pharmaceutically significant, natural products, derivatives, human rhinovirus 3c protease, conjugate addition, antidiabetic activity
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