Bioactive Diopside (CaMgSi2O6) as a Drug Delivery Carrier – A Review

Author(s): C. Saravanan, S. Sasikumar.

Journal Name: Current Drug Delivery

Volume 9 , Issue 6 , 2012

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The bone infections are the most divesting complications confronted by the physicians and patients. The antibiotic loaded bone cements, such as synthetic ceramics and natural ceramics were accepted for bone infections. The currently available bone cements were not accepted due to the lack of mechanical strength, porosity and quick degradation rate etc. The major aim of this review is to discuss about several different synthetic methods used to prepare the bioactive diopside (CaMgSi2O6) and its applications in ceramic drug delivery systems for controlled and targeted delivery. It has been reported from various research articles, diopside was mainly used for bone tissue regeneration, dentistry, orthopedics and enzyme delivery matrices with different formulations. Compared to other bioceramics diopside is preferable due to its biocompatibility and high mechanical strength.

Keywords: Diopside, Sol-gel synthesis, Microspheres, Bioactivity, Drug delivery system

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Article Details

Year: 2012
Page: [583 - 587]
Pages: 5
DOI: 10.2174/156720112803529765
Price: $65

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PDF: 15