Abstract
The bone infections are the most divesting complications confronted by the physicians and patients. The antibiotic loaded bone cements, such as synthetic ceramics and natural ceramics were accepted for bone infections. The currently available bone cements were not accepted due to the lack of mechanical strength, porosity and quick degradation rate etc. The major aim of this review is to discuss about several different synthetic methods used to prepare the bioactive diopside (CaMgSi2O6) and its applications in ceramic drug delivery systems for controlled and targeted delivery. It has been reported from various research articles, diopside was mainly used for bone tissue regeneration, dentistry, orthopedics and enzyme delivery matrices with different formulations. Compared to other bioceramics diopside is preferable due to its biocompatibility and high mechanical strength.
Keywords: Diopside, Sol-gel synthesis, Microspheres, Bioactivity, Drug delivery system
Current Drug Delivery
Title:Bioactive Diopside (CaMgSi2O6) as a Drug Delivery Carrier – A Review
Volume: 9 Issue: 6
Author(s): C. Saravanan and S. Sasikumar
Affiliation:
Keywords: Diopside, Sol-gel synthesis, Microspheres, Bioactivity, Drug delivery system
Abstract: The bone infections are the most divesting complications confronted by the physicians and patients. The antibiotic loaded bone cements, such as synthetic ceramics and natural ceramics were accepted for bone infections. The currently available bone cements were not accepted due to the lack of mechanical strength, porosity and quick degradation rate etc. The major aim of this review is to discuss about several different synthetic methods used to prepare the bioactive diopside (CaMgSi2O6) and its applications in ceramic drug delivery systems for controlled and targeted delivery. It has been reported from various research articles, diopside was mainly used for bone tissue regeneration, dentistry, orthopedics and enzyme delivery matrices with different formulations. Compared to other bioceramics diopside is preferable due to its biocompatibility and high mechanical strength.
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Cite this article as:
Saravanan C. and Sasikumar S., Bioactive Diopside (CaMgSi2O6) as a Drug Delivery Carrier – A Review, Current Drug Delivery 2012; 9 (6) . https://dx.doi.org/10.2174/156720112803529765
DOI https://dx.doi.org/10.2174/156720112803529765 |
Print ISSN 1567-2018 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5704 |
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