Translational Animal Models in Drug Discovery and Development

Editor(s): Xinkang Wang

Indexed in: Scopus

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Animal models of diseases play a pivotal role in drug discovery and development, not only for proof of the concept studies of efficacy, PK/PD relationship but also for drug safety assessment. Since ...
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Pp. i-iii (3)

Giora Feuerstein



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Xinkang Wang



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Xinkang Wang



Animal Models of Atherosclerosis and Spontaneous Plaque Rupture

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Andrew R. Bond and Christopher L. Jackson


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Animal Models of Ischemic Stroke: Issues in Translational Congruency

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Frank C. Barone, Daniel M. Rosenbaum, Jie Li, Jin Zhou and Xinkang Wang


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Mouse Models of Coagulation Factor Deficiencies for Translational Research

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Meghann P. McManus and David Gailani


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Xenograft Models of the Normal and Malignant Human Breast  Open Access Plus

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Michael T. Lewis



BALB-neuT Female Mice as a Dynamic Model of Mammary Cancer

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Manuela Iezzi, Raffaele A. Calogero, Michela Spadaro, Piero Musiani, Guido Forni and Federica Cavallo


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Modeling Human Asthma in Animals

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Jason H.T. Bates, Mercedes Rincon and Charles G. Irvin


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In Vivo Veritas: Preclinical Models of Human Arthritic Disease in Non-Human Primates

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Michel Vierboom and Elia Breedveld


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Xinkang Wang