We proposed a method of synthesis to produce [11C]Choline using TRACERlab FXc module that utilized gas
phase iodination. The product had radiochemical purity of 99.79 + 0.14 % and specific activity of 45.7 + 7.59 GBq/mol.
[11C]Choline did not have at the moment a specific monograph in European Pharmacopeia therefore we used, when possible,
as quality controls reference the monograph of [18F]FDG and we proposed suitable methods to verify radiochemical
purity and to quantify residual DMAE and choline amounts.
Keywords: [11C]CH3I, [11C]Choline, gas phase iodination, prostate cancer, PET, quality controls, radiopharmaceutical,
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