Natural products have not only yielded new and effective drugs but have also provided insight into new mechanisms of action.
Paclitaxel (Taxol) as the first promoters of tubulin polymerization plays important roles in the war against cancer and in the exploring
new microtubule-binding drugs. The present review summarized the development of paclitaxel and its analogues which can be used as
the precurce of synthesis of Taxol and its analogues.
Keywords: Taxol, taxol analogy, taxane, Taxus, anti-cancer, proliferation, phenotype, heredity, motherapeutic, radiotherapy
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