Polymeric Nanoparticles of FMISO: Are Nano-Radiopharmaceuticals Better Than Conventional Ones?

Author(s): Marta de Souza Albernaz, Beatriz Ferreira de Carvalho Patricio, Gilberto Weissmuller, Franceline Reynaud, Tom CH Adamsen, Ralph Santos-Oliveira.

Journal Name: Current Radiopharmaceuticals

Volume 5 , Issue 4 , 2012

Abstract:

Nanotechnology has been the last frontier in the diagnoses and treatment of many diseases, especially in oncology. The use of nanoparticles of radiopharmaceuticals may represent the future of Nuclear Medicine. In this study we developed, characterized and tested polymeric nanoparticles of FMISO (fluoromisonidazole) in a dynamic study of biodistribution. The results of the development as characterization showed that nanoparticles were well obtained with a size range of 300- 500nm and a spherical shape.

Keywords: Radiopharmaceuticals, Oncology, Nuclear Medicine, Hypoxia, Predictive.

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Article Details

VOLUME: 5
ISSUE: 4
Year: 2012
Page: [336 - 339]
Pages: 4
DOI: 10.2174/1874471011205040336
Price: $58

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