Brain Connectivity Studies in Schizophrenia: Unravelling the Effects of Antipsychotics

Author(s): Ayna B. Nejad, Bjorn H. Ebdrup, Birte Y. Glenthoj, Hartwig R. Siebner.

Journal Name: Current Neuropharmacology

Volume 10 , Issue 3 , 2012

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Abstract:

Impaired brain connectivity is a hallmark of schizophrenia brain dysfunction. However, the effect of drug treatment and challenges on the dysconnectivity of functional networks in schizophrenia is an understudied area. In this review, we provide an overview of functional magnetic resonance imaging studies examining dysconnectivity in schizophrenia and discuss the few studies which have also attempted to probe connectivity changes with antipsychotic drug treatment. We conclude with a discussion of possible avenues for further investigation.

Keywords: Antipsychotic drug treatment, brain connectivity, fMRI, schizophrenia

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Article Details

VOLUME: 10
ISSUE: 3
Year: 2012
Page: [219 - 230]
Pages: 12
DOI: 10.2174/157015912803217305
Price: $58

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