Dendrimers in Cancer Therapeutics and Diagnosis
Rui Guo and Xiangyang Shi
Pages 1097-1109 (13)
Dendrimers represent a class of monodispersed synthetic macromolecules with a well defined three-dimensional structure of
nanometer dimension in which a series of layered branches regularly extend from a central core molecule. Due to their precise nanoscale
sizes, well-defined branched structures, and various surface modifications, dendrimers have been extensively investigated in a wide range
of applications in the biomedical field, particularly in the therapeutics and diagnosis of cancer. This article gives an overview of the recent
advances of dendrimers and dendrimer-based hybrid nanoparticles for cancer therapeutics and diagnosis applications.
Dendrimer, anticancer drug delivery, cancer diagnosis, nanometer, Hybrid, Nanomedicine, gene regulation, dendritic branches, linear polymers, bioassemblies
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Donghua University, Shanghai 201620, People’s Republic of China.