Reaction of 3-acetyl and 3-bromoacetyl coumarins with hydrazine hydrate has resulted in the ring opening of
the coumarin moiety. The reaction was attempted with a view to obtain some new pyridazinones and pyrazolones. The reaction
did not proceed via the expected pathway instead led to the formation of salicyl azines, the structure of which has
been confirmed by single crystal X-ray studies.
Keywords: 3-Acetylcoumarins, 3-bromoacetyl coumarins, 4-bromomethyl coumarins, de-acylation, ring opening, hydrate, pyrazolones, coumarins, nucleophiles, amidation.
Rights & PermissionsPrintExport