Dermatological Treatments

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Dermatological treatments have changed continuously throughout recent decades. Old drugs are recognized as being effective in new indications and new methods of dosage or application have been ...
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Systemic Retinoids

Pp. 261-274 (14)

Beatriz Aranegui and Alberto Conde-Taboada

Abstract

Systemic retinoids are drugs specifically employed in dermatology, with only isolated indications in other specialties. Nevertheless, they have effects on different organs different from skin, and dermatologists should be aware of these effects. In this chapter four drugs are reviewed: isotretinoin, acitretin, alitretinoin and bexarotene. There is a wide spectrum of conditions responsive to systemic retinoids: acne, psoriasis, eczema, cutaneous lymphoma… etc. and they are important instruments in their therapy, once adverse effects have been controlled. An individualized assessment has been performed, mainly on the indications and adverse events, due to the differences among them.

Keywords:

Retinoids, acitretin, etretinate, isotretinoin, retinaldehide, vitamin A, tretinoin, administration, oral, skin and connective tissue diseases, dermatologic agents, skin diseases skin.

Affiliation:

Dermatology Department, Complexo Hospitalario Pontevedra, Pontevedra, Spain