Cachexia and Herbal Medicine: Perspective
Hajime Suzuki, Akihiro Asakawa, Haruka Amitani, Norifumi Nakamura and Akio Inui
Affiliation: Department of Psychosomatic Internal Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8520, Japan.
Kampo, a form of traditional herbal medical practice, has become a substance of interest for scientific research. Although earlier
clinical reports concerning Kampo are abundant, the scientific investigation of Kampo has a very short history. However, the process
of acquiring quantifiable clinical trial evidence on herbal medicine is now clearly underway. The development of multi-component herbal
medicines capable of targeting multiple sites could be useful both for future drug discovery and for the potential management of complex
diseases. Additionally, mechanistic studies and the identification of active compounds could lead to new discoveries in the biological and
biomedical sciences. Modern translational research on herbal medicines beyond basic science and clinical perspectives will contribute to
the development of new medicines. This review covers the translational aspects of herbal medicine with a focus on cancer anorexiacachexia.
The review gives perspective on a new horizon for herbal medicine from a scientific point of view and a basis for the further
development of complementary and alternative medicine (CAM) for patients.
Keywords: Cancer anorexia-cachexia syndrome, complementary and alternative medicine, herbal medicine, Kampo, feeding-regulatory
peptide, sarcopenia, cytokine, translational approach, active compounds, complementary and alternative medicine (CAM).
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