Chemical Constituents of Plants from the Genus Forsythia

Author(s): Qing Zhang, Chenhong Jia, Haiyun Xu, Yufang Wang, Manli Zhang, Changhong Huo, Qingwen Shi, Shuhong Yu.

Journal Name: Mini-Reviews in Organic Chemistry

Volume 9 , Issue 3 , 2012

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Abstract:

The genus of Forsythia (Oleaceae), composing ca. 10~15 species, is mostly native to eastern Asia and used in oriental traditional medicines. Phytochemical investigations on Forsythia species have shown that triterpenoids, lignans, flavonoids, phenylethanoid glycosides and C6-C2 natural alcohols, accumulated mainly in the fruits, are the major components. Many studies have elucidated that phenolic compounds, including lignans, phenylethanoid glycosides and flavonoids are responsible for the various biological activities of the herbal medicine. This review lists 141 chemical constituents as well as their biosynthetic pathway, bioactivities and quality control as reported until September, 2011 (104 references).

Keywords: Forsythia, chemical constituents, lignans, phenylethanoid glycosides, C6-C2 natural alcohols, biosynthesis, bioactivities, quality control.

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Article Details

VOLUME: 9
ISSUE: 3
Year: 2012
Page: [303 - 318]
Pages: 16
DOI: 10.2174/1570193X11209030303
Price: $58

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