Current Cancer Therapy Reviews

Kurt S. Zaenker
Institute of Immunology and Experimental Oncology University Witten/Herdecke
Stockumerstraße 10, 58448 Witten
Germany

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Ductal Carcinoma In Situ: Clinical Trials Update and Resolving Controversies

Author(s): Robert E. Roses, Henry M. Kuerer.

Abstract:

The diagnosis of ductal carcinoma in situ (DCIS) has increased dramatically following the widespread adoption of screening mammography. DCIS has a favorable prognosis overall, but is associated with an increased risk of invasive breast cancer (IBC) and occasionally, with poor outcomes. The goal of the multidisciplinary treatment of DCIS is to prevent the development of invasive disease. The identification of patients at elevated risk for progression or recurrence who require more aggressive multimodality therapy and, conversely, those who can safely forgo elements of the current therapeutic armamentarium are important current challenges.

Keywords: Ductal Carcinoma in Situ, DCIS, Controversies, Clinical Trials

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Article Details

VOLUME: 8
ISSUE: 3
Year: 2012
Page: [182 - 188]
Pages: 7
DOI: 10.2174/157339412802653173
Price: $58