Current Immune Therapies of Autoimmune Disease of the Nervous System with Special Emphasis to Multiple Sclerosis
Autoimmune diseases of the nervous system such as myasthenia gravis, inflammatory demyelinating polyneuropathies, multiple
sclerosis and others are still not curable. Yet the introduction of modern immune therapies could significantly improve the prospects
of many patients affected by these disorders. In addition to steroids and immunosuppression i.v. immunoglobulins are used for treatment
of myasthenia gravis and chronic inflammatory demyelinating polyneuropathy. Interferons, glatiramer acetate, natalizumab and fingolimod
are applied in multiple sclerosis. The ever-improving efficacy of the drugs has to be balanced against the increasing risk of possible
severe adverse effects.
Keywords: Nervous system, autoimmune disease, myasthenia gravis, inflammatory demyelinating polyneuropathy, multiple sclerosis, interferon, glatiramerazetat, natalizumab, fingolimod, drugs.
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