Abstract
The hypothalamus and posterior pituitary form a complex neurohumoral system playing a key role in maintaining body fluid homeostasis and reproductive function. We review the pathophysiology mechanisms of posterior pituitary hormones and their implications, beyond water balance and delivery, in social functioning, pair bonding and affiliative behavior. Actual and future treatments for neurohypophysis related disorders are also discussed, particularly focusing on the development of new therapeutic compounds and patents.
Keywords: Hypothalamus, neurohypophysis, oxytocin, pituitary, treatment, vasopressin.
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery
Title:The Hypothalamic-Neurohypophyseal System: Current and Future Treatment of Vasopressin and Oxytocyn Related Disorders
Volume: 6 Issue: 3
Author(s): Rocco S.Calabro, Domenico Italiano, Danilo Ferrara, Stefania Mondello, Valeria Conti-Nibali, Carlo Salviera and Placido Bramanti
Affiliation:
Keywords: Hypothalamus, neurohypophysis, oxytocin, pituitary, treatment, vasopressin.
Abstract: The hypothalamus and posterior pituitary form a complex neurohumoral system playing a key role in maintaining body fluid homeostasis and reproductive function. We review the pathophysiology mechanisms of posterior pituitary hormones and their implications, beyond water balance and delivery, in social functioning, pair bonding and affiliative behavior. Actual and future treatments for neurohypophysis related disorders are also discussed, particularly focusing on the development of new therapeutic compounds and patents.
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Cite this article as:
S.Calabro Rocco, Italiano Domenico, Ferrara Danilo, Mondello Stefania, Conti-Nibali Valeria, Salviera Carlo and Bramanti Placido, The Hypothalamic-Neurohypophyseal System: Current and Future Treatment of Vasopressin and Oxytocyn Related Disorders, Recent Patents on Endocrine, Metabolic & Immune Drug Discovery 2012; 6 (3) . https://dx.doi.org/10.2174/187221412802481720
DOI https://dx.doi.org/10.2174/187221412802481720 |
Print ISSN 1872-2148 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3334 |
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