Epidemiology of Type 2 Diabetes

Indexed in: Scopus

This e-book on diabetes epidemiology starts with the evolution in the diagnostic criteria for diabetes, particularly the changes in the last 15 years and their impact on the prevalence of the ...
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Diabetes and Cancer Epidemiology

Pp. 98-104 (7)

Xianghai Zhou

Abstract

It has been proposed that diabetes was associated with an increased risk of cancer mortality and morbidity. Complex mechanisms are involved in the association between diabetes and cancer. Metformin has been suggested to reduce the risk of cancer incidence (Hazard ratio 0.63 (95% CI 0.53- 0.75)) or cancer mortality (Hazard ratio 0.43 (95% CI 0.23-0.80)), but insulin or sulfonylurea is suspected to increase the risk of cancer incidence (Hazard ratio 1.36 (95% CI 1.19-1.54)) or cancer mortality (Hazard ratio 1.30 (95% CI 1.10-1.60)). Evidences on these issues are reviewed and summarized in this chapter.

Keywords:

Diabetes, anti-diabetic drugs, cancer motality and morbidity.

Affiliation:

Department of Endocrinology and Metabolism, Peking University People’s Hospital, 11 Xizhimen South Street, 100044, Beijing, China and Department of Public Health, Hjelt Institute, University of Helsinki, PL41, Mannerheimintie 172, 00014, Helsinki, Finland