On-Chip Pretreatment of Whole Blood by Using MEMS Technology

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The Microfabrication technology has stimulated a plurality of lab-on-a-chip research for biomedical researchers and health care practitioners to manipulate and analyze complex biological fluids at ...
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Introduction of Microfluidic Chips Targeting Whole Blood Pretreatment

Pp. 3-7 (5)

Xing Chen, Dafu Cui and Jian Chen

Abstract

The development of micro-total analysis systems targeting blood sample detections requests the availability of microfluidic devices for whole blood sample pretreatment including blood cell and plasma separation, white blood cell lysis and DNA purification, to name a few. In this chapter, background introduction of whole blood samples is conducted followed by a summary of key features and historical development of microfluidics. The marriage of microfluidics and whole blood pretreatment is highlighted with advantages and potential concerns discussed in detail.

Keywords:

Microfluidics, sample pretreatment, whole blood.

Affiliation:

State Key Laboratory of Transducer Technology, Institute of Electronics, Chinese Academy of Sciences, Beijing 100190, China