Revisit: Eaton’s Reagent Catalyzed Synthesis of Mono and Bis-Chalcone Derivatives

Author(s): Shrikrishna. D. Tupare, Santosh V. Nalage, Sharad R. Bobe, Shivshankar N. Hallale, Sheshanath V. Bhosale, Sanjay K. Vyawahare, Satish A. Dake, Sidhanath V. Bhosale, Rajendra P. Pawar.

Journal Name: Letters in Organic Chemistry

Volume 9 , Issue 7 , 2012

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Abstract:

Eaton’s reagent efficiently catalyzed the Claisen-Schmidt condensation reaction of aryl aldehydes with aromatic and cyclic ketones under solvent free microwave irradiation conditions to afford mono and bis-chalcone derivatives. The present approach offers several advantages such as shorter reaction times, cleaner reactions, good yields, inexpensive reagent and mild reaction conditions.

Keywords: Aromatic aldehydes, aromatic ketone, chalcones, cyclic ketone, eaton’s reagent, solvent-free, fused pyridines, thiazines, pyrimidines, iodine

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Article Details

VOLUME: 9
ISSUE: 7
Year: 2012
Page: [526 - 529]
Pages: 4
DOI: 10.2174/157017812802139627

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