Subtype-Selective Dopamine Receptor Radioligands for PET Imaging: Current Status and Recent Developments

Author(s): A. Banerjee, O. Prante.

Journal Name: Current Medicinal Chemistry

Volume 19 , Issue 23 , 2012

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Abstract:

This review presents a general overview of the subtype-selective dopamine receptor radioligands for in vivo imaging of dopamine receptor expression by positron emission tomography (PET). Besides the 11C- and 18F-labeled radioligands which are already in clinical use, a summary of subtype-selective radioligands which had been studied in vitro and in vivo is provided, which shines light onto the current status and recent developments in this field of radiopharmaceutical research.

Keywords: Dopamine, D2, D3, D4, dopamine receptor, selectivity, subtype-selectivity, positron emission tomography, PET, radioligand, PET ligand, radiopharmaceutical, F-18, C-11

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Article Details

VOLUME: 19
ISSUE: 23
Year: 2012
Page: [3957 - 3966]
Pages: 10
DOI: 10.2174/092986712802002518
Price: $58

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