The most important radioisotope for use in Nuclear Medicine is 99mTc, supplied in the form of a 99Mo/99mTc
generator. After the supply crisis of 99Mo starting in 2008 the availability of 99Mo became a worldwide concern. The purpose
of this work is to do a brief story of the availability of 99Mo in the world followed by an overview of the production
routes of 99Mo and the generators technology.
Keywords: Fission of 235U, Molybdenum-99, Nuclear Reactor, Particle Accelerator, Radioisotope generator, Technetium-99m, HEU, LEU, GTRI/DOE efforts
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